Vitamin D Supplement Doses and Serum 25-Hydroxyvitamin D in the Range Associated with Cancer Prevention
Cedric F. Garland, Christine B. French, Leo L. Baggerly, and Robert P. Heaney
The recent increase in interest in vitamin D by the general public has fueled a better than 200% increase in sales of overthe-counter vitamin D preparations from 2008 to 2009, and a more than 6-fold increase since 2001 (1). Additionally, products with progressively increasing content of vitamin D have been introduced with similar rapidity. There seems to have been little precedent for a change of this magnitude and duration for other nutrients (e.g., vitamins C and E) that have enjoyed brief periods of popularity among the general public. There is essentially no
information on how the public uses these products or on their impact on the vitamin D status of consumers.
GrassrootsHealth (GRH), a non-profit community service organization dedicated to promoting public awareness about vitamin D, has assembled a database that includes information on supplemental vitamin D intake by a selfselected population cohort, and links these intakes to measured values for serum 25(OH)D, various demographic
variables, and a variety of health status measures. GRH data include values from many individuals with daily supplemental intakes in and above the ranges often used today for cancer prevention and co-therapy (2, 3).
This study used the GRH database to describe the relationship of measured vitamin D status to vitamin D supplementation, both as practiced by health conscious individuals and as related to cancer prevention.
Dimensions: 8.5 x 11 inches